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Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity
Intracerebral injection of the excitotoxic, endogenous tryptophan metabolite, quinolinic acid (QA), constitutes a chemical model of neurodegenerative brain disease. Complementary techniques were combined to examine the consequences of QA injection into medial prefrontal cortex (mPFC) of C57BL6 mice....
Autores principales: | Latif-Hernandez, Amira, Shah, Disha, Ahmed, Tariq, Lo, Adrian C., Callaerts-Vegh, Zsuzsanna, Van der Linden, Annemie, Balschun, Detlef, D’Hooge, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098239/ https://www.ncbi.nlm.nih.gov/pubmed/27819338 http://dx.doi.org/10.1038/srep36489 |
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