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Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow

Disseminated prostate cancer (PCa) cells in the marrow survive for years without evidence of proliferation, while maintaining the capacity to develop into metastatic lesions. These dormant disseminated tumor cells (DTCs) may reside in close proximity to osteoblasts, while expressing high levels of A...

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Detalles Bibliográficos
Autores principales: Yumoto, Kenji, Eber, Matthew R., Wang, Jingcheng, Cackowski, Frank C., Decker, Ann M., Lee, Eunsohl, Nobre, Ana Rita, Aguirre-Ghiso, Julio A., Jung, Younghun, Taichman, Russell S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098246/
https://www.ncbi.nlm.nih.gov/pubmed/27819283
http://dx.doi.org/10.1038/srep36520