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High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly diagnosed symptomatic multiple myeloma

Periostin is an extracellular matrix protein that is implicated in the biology of normal bone remodeling and in different cancer cell growth and metastasis. However, there is no information on the role of periostin in multiple myeloma (MM). Thus, we evaluated periostin in six myeloma cell lines in v...

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Detalles Bibliográficos
Autores principales: Terpos, E, Christoulas, D, Kastritis, E, Bagratuni, T, Gavriatopoulou, M, Roussou, M, Papatheodorou, A, Eleutherakis-Papaiakovou, E, Kanellias, N, Liakou, C, Panagiotidis, I, Migkou, M, Kokkoris, P, Moulopoulos, L A, Dimopoulos, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098262/
https://www.ncbi.nlm.nih.gov/pubmed/27716740
http://dx.doi.org/10.1038/bcj.2016.90