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High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly diagnosed symptomatic multiple myeloma
Periostin is an extracellular matrix protein that is implicated in the biology of normal bone remodeling and in different cancer cell growth and metastasis. However, there is no information on the role of periostin in multiple myeloma (MM). Thus, we evaluated periostin in six myeloma cell lines in v...
Autores principales: | Terpos, E, Christoulas, D, Kastritis, E, Bagratuni, T, Gavriatopoulou, M, Roussou, M, Papatheodorou, A, Eleutherakis-Papaiakovou, E, Kanellias, N, Liakou, C, Panagiotidis, I, Migkou, M, Kokkoris, P, Moulopoulos, L A, Dimopoulos, M A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098262/ https://www.ncbi.nlm.nih.gov/pubmed/27716740 http://dx.doi.org/10.1038/bcj.2016.90 |
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