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Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers
INTRODUCTION: Lesinurad is a selective uric acid reabsorption inhibitor approved for the treatment of gout in combination with a xanthine oxidase inhibitor (XOI) in patients who have not achieved target serum uric acid (sUA) levels with an XOI alone. Most people with gout have chronic kidney disease...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098526/ https://www.ncbi.nlm.nih.gov/pubmed/27843295 http://dx.doi.org/10.2147/DDDT.S119944 |