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Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers

INTRODUCTION: Lesinurad is a selective uric acid reabsorption inhibitor approved for the treatment of gout in combination with a xanthine oxidase inhibitor (XOI) in patients who have not achieved target serum uric acid (sUA) levels with an XOI alone. Most people with gout have chronic kidney disease...

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Detalles Bibliográficos
Autores principales:	Gillen, Michael, Valdez, Shakti, Zhou, Dongmei, Kerr, Bradley, Lee, Caroline A, Shen, Zancong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098526/ https://www.ncbi.nlm.nih.gov/pubmed/27843295 http://dx.doi.org/10.2147/DDDT.S119944

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