Cargando…

Fenretinide inhibits macrophage inflammatory mediators and controls hypertension in spontaneously hypertensive rats via the peroxisome proliferator-activated receptor gamma pathway

Fenretinide is a novel anticancer agent reported to exhibit anti-invasive and antimetastatic activities. It has also been shown to improve obesity and diabetes, although the effects of fenretinide on hypertension are still unknown, and the detailed mechanisms remain unclear. In this study, we have s...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Ching-Han, Lee, Shang-Yu, Zhang, Chun-Cheng, Du, Ye-Fong, Hung, Hao-Chang, Wu, Hung-Tsung, Ou, Horng-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098527/
https://www.ncbi.nlm.nih.gov/pubmed/27843299
http://dx.doi.org/10.2147/DDDT.S114879