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Fenretinide inhibits macrophage inflammatory mediators and controls hypertension in spontaneously hypertensive rats via the peroxisome proliferator-activated receptor gamma pathway
Fenretinide is a novel anticancer agent reported to exhibit anti-invasive and antimetastatic activities. It has also been shown to improve obesity and diabetes, although the effects of fenretinide on hypertension are still unknown, and the detailed mechanisms remain unclear. In this study, we have s...
Autores principales: | Lin, Ching-Han, Lee, Shang-Yu, Zhang, Chun-Cheng, Du, Ye-Fong, Hung, Hao-Chang, Wu, Hung-Tsung, Ou, Horng-Yih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098527/ https://www.ncbi.nlm.nih.gov/pubmed/27843299 http://dx.doi.org/10.2147/DDDT.S114879 |
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