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Fine-mapping cellular QTLs with RASQUAL and ATAC-seq
When cellular traits are measured using high-throughput DNA sequencing quantitative trait loci (QTLs) manifest as fragment count differences between individuals and allelic differences within individuals. We present RASQUAL (Robust Allele Specific QUAntitation and quality controL), a novel statistic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098600/ https://www.ncbi.nlm.nih.gov/pubmed/26656845 http://dx.doi.org/10.1038/ng.3467 |