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Fine-mapping cellular QTLs with RASQUAL and ATAC-seq

When cellular traits are measured using high-throughput DNA sequencing quantitative trait loci (QTLs) manifest as fragment count differences between individuals and allelic differences within individuals. We present RASQUAL (Robust Allele Specific QUAntitation and quality controL), a novel statistic...

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Detalles Bibliográficos
Autores principales: Kumasaka, Natsuhiko, Knights, Andrew J, Gaffney, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098600/
https://www.ncbi.nlm.nih.gov/pubmed/26656845
http://dx.doi.org/10.1038/ng.3467