APPL1-Mediating Leptin Signaling Contributes to Proliferation and Migration of Cancer Cells

Leptin has been implicated in tumorigenesis and tumor progression, particularly in obese patients. As a multifunctional adaptor protein, APPL1 (containing pleckstrin homology domain, phosphotyrosine binding domain, and a leucine zipper motif 1) plays a critical role in regulating adiponectin and ins...

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Detalles Bibliográficos
Autores principales: Ding, Youming, Cao, Yingkang, Wang, Bin, Wang, Lei, Zhang, Yemin, Zhang, Deling, Chen, Xiaoyan, Li, Mingxin, Wang, Changhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098739/
https://www.ncbi.nlm.nih.gov/pubmed/27820851
http://dx.doi.org/10.1371/journal.pone.0166172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098739/
https://www.ncbi.nlm.nih.gov/pubmed/27820851
http://dx.doi.org/10.1371/journal.pone.0166172

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