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EGR1 Regulates Transcription Downstream of Mechanical Signals during Tendon Formation and Healing

BACKGROUND: Tendon is a mechanical tissue that transmits forces generated by muscle to bone in order to allow body motion. The molecular pathways that sense mechanical forces during tendon formation, homeostasis and repair are not known. EGR1 is a mechanosensitive transcription factor involved in te...

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Detalles Bibliográficos
Autores principales: Gaut, Ludovic, Robert, Nicolas, Delalande, Antony, Bonnin, Marie-Ange, Pichon, Chantal, Duprez, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098749/
https://www.ncbi.nlm.nih.gov/pubmed/27820865
http://dx.doi.org/10.1371/journal.pone.0166237