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CENP-A and H3 Nucleosomes Display a Similar Stability to Force-Mediated Disassembly

Centromere-specific nucleosomes are a central feature of the kinetochore complex during mitosis, in which microtubules exert pulling and pushing forces upon the centromere. CENP-A nucleosomes have been assumed to be structurally unique, thereby providing resilience under tension relative to their H3...

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Detalles Bibliográficos
Autores principales: Kim, Sung Hyun, Vlijm, Rifka, van der Torre, Jaco, Dalal, Yamini, Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098787/
https://www.ncbi.nlm.nih.gov/pubmed/27820823
http://dx.doi.org/10.1371/journal.pone.0165078