Metformin Ameliorates Dysfunctional Traits of Glibenclamide- and Glucose-Induced Insulin Secretion by Suppression of Imposed Overactivity of the Islet Nitric Oxide Synthase-NO System

Metformin lowers diabetic blood glucose primarily by reducing hepatic gluconeogenesis and increasing peripheral glucose uptake. However, possible effects by metformin on beta-cell function are incompletely understood. We speculated that metformin might positively influence insulin secretion through...

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Detalles Bibliográficos
Autores principales: Lundquist, Ingmar, Mohammed Al-Amily, Israa, Meidute Abaraviciene, Sandra, Salehi, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098820/
https://www.ncbi.nlm.nih.gov/pubmed/27820841
http://dx.doi.org/10.1371/journal.pone.0165668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098820/
https://www.ncbi.nlm.nih.gov/pubmed/27820841
http://dx.doi.org/10.1371/journal.pone.0165668

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