Association of Cytochrome P450 Genetic Variants with Clopidogrel Resistance and Outcomes in Acute Ischemic Stroke

Aims: Clopidogrel is an antiplatelet drug primarily used to treat or prevent acute ischemic stroke (IS) or myocardial infarction (MI). This prodrug requires biotransformation to an active metabolite by cytochrome P450 (CYP) enzymes, and CYP single nucleotide polymorphisms (SNPs) could affect the eff...

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Detalles Bibliográficos
Autores principales: Yi, Xingyang, Lin, Jing, Wang, Yanfen, Zhou, Qiang, Wang, Chun, Cheng, Wen, Chi, Lifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098919/
https://www.ncbi.nlm.nih.gov/pubmed/26961113
http://dx.doi.org/10.5551/jat.33290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098919/
https://www.ncbi.nlm.nih.gov/pubmed/26961113
http://dx.doi.org/10.5551/jat.33290

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