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Iron Together with Lipid Downregulates Protein Levels of Ceruloplasmin in Macrophages Associated with Rapid Foam Cell Formation

Aim: Iron accumulation in foam cells was previously shown to be involved in atherogenesis. However, the mechanism for iron accumulation was not clarified. Ceruloplasmin (Cp) is an important factor in cellular iron efflux and was found to be downregulated in atherosclerotic plaques in our previous st...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Ji, Jiajie, Hao, Shuangying, Zhang, Meng, Li, Kuanyu, Qiao, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098920/
https://www.ncbi.nlm.nih.gov/pubmed/27040361
http://dx.doi.org/10.5551/jat.32292