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Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptide
Amyloid β (Aβ) peptide is present as a major component in amyloid plaque that is one of the hallmarks of Alzheimer's disease. The peptide contains a single tyrosine residue and Aβ has a major implication in the pathology of the disease progression. Current investigation revealed that the tyrosi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098961/ https://www.ncbi.nlm.nih.gov/pubmed/27853536 http://dx.doi.org/10.1098/rsos.160112 |