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Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptide

Amyloid β (Aβ) peptide is present as a major component in amyloid plaque that is one of the hallmarks of Alzheimer's disease. The peptide contains a single tyrosine residue and Aβ has a major implication in the pathology of the disease progression. Current investigation revealed that the tyrosi...

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Detalles Bibliográficos
Autores principales: Das, Swagata, Das, Supriya, Roy, Anupam, Pal, Uttam, Maiti, Nakul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098961/
https://www.ncbi.nlm.nih.gov/pubmed/27853536
http://dx.doi.org/10.1098/rsos.160112

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