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The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation

The primary cilium is an antenna-like, microtubule-based organelle on the surface of most vertebrate cells for receiving extracellular information. Although primary cilia form in the quiescent phase, ciliary disassembly occurs when quiescent cells re-enter the proliferative phase. It was shown that...

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Detalles Bibliográficos
Autores principales: Miyamoto, Tatsuo, Hosoba, Kosuke, Ochiai, Hiroshi, Royba, Ekaterina, Izumi, Hideki, Sakuma, Tetsushi, Yamamoto, Takashi, Dynlacht, Brian David, Matsuura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099117/
https://www.ncbi.nlm.nih.gov/pubmed/25660017
http://dx.doi.org/10.1016/j.celrep.2015.01.003