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The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation
The primary cilium is an antenna-like, microtubule-based organelle on the surface of most vertebrate cells for receiving extracellular information. Although primary cilia form in the quiescent phase, ciliary disassembly occurs when quiescent cells re-enter the proliferative phase. It was shown that...
Autores principales: | Miyamoto, Tatsuo, Hosoba, Kosuke, Ochiai, Hiroshi, Royba, Ekaterina, Izumi, Hideki, Sakuma, Tetsushi, Yamamoto, Takashi, Dynlacht, Brian David, Matsuura, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099117/ https://www.ncbi.nlm.nih.gov/pubmed/25660017 http://dx.doi.org/10.1016/j.celrep.2015.01.003 |
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