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Imaging the NADH:NAD(+) Homeostasis for Understanding the Metabolic Response of Mycobacterium to Physiologically Relevant Stresses
The NADH:NAD(+) ratio is the primary indicator of the metabolic state of bacteria. NAD(H) homeostasis is critical for Mycobacterium tuberculosis (Mtb) survival and is thus considered an important drug target, but the spatio-temporal measurements of NAD(H) remain a challenge. Genetically encoded fluo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099167/ https://www.ncbi.nlm.nih.gov/pubmed/27878107 http://dx.doi.org/10.3389/fcimb.2016.00145 |