Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies and is projected to be the second leading cause of cancer-related death by 2030. Despite extensive knowledge and insights into biological properties and genetic aberrations of PDAC, therapeutic options rema...

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Detalles Bibliográficos
Autores principales: Mahajan, Ujjwal M, Teller, Steffen, Sendler, Matthias, Palankar, Raghavendra, van den Brandt, Cindy, Schwaiger, Theresa, Kühn, Jens-Peter, Ribback, Silvia, Glöckl, Gunnar, Evert, Matthias, Weitschies, Werner, Hosten, Norbert, Dombrowski, Frank, Delcea, Mihaela, Weiss, Frank-Ulrich, Lerch, Markus M, Mayerle, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099195/
https://www.ncbi.nlm.nih.gov/pubmed/27196585
http://dx.doi.org/10.1136/gutjnl-2016-311393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099195/
https://www.ncbi.nlm.nih.gov/pubmed/27196585
http://dx.doi.org/10.1136/gutjnl-2016-311393

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