Developmental profiling of ASD-related shank3 transcripts and their differential regulation by valproic acid in zebrafish

SHANK3 is a scaffolding protein that binds to various synaptic proteins at the postsynaptic density (PSD) of excitatory glutamatergic synapses. SHANK3 is not only strongly implicated in autism spectrum disorders (ASD) but also plays a critical role in human Phelan-McDermid syndrome (22q13.3 deletion...

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Detalles Bibliográficos
Autores principales: Liu, Chun-xue, Peng, Xiao-lan, Hu, Chun-chun, Li, Chun-yang, Li, Qiang, Xu, Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099374/
https://www.ncbi.nlm.nih.gov/pubmed/27562614
http://dx.doi.org/10.1007/s00427-016-0561-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099374/
https://www.ncbi.nlm.nih.gov/pubmed/27562614
http://dx.doi.org/10.1007/s00427-016-0561-4

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