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Developmental profiling of ASD-related shank3 transcripts and their differential regulation by valproic acid in zebrafish
SHANK3 is a scaffolding protein that binds to various synaptic proteins at the postsynaptic density (PSD) of excitatory glutamatergic synapses. SHANK3 is not only strongly implicated in autism spectrum disorders (ASD) but also plays a critical role in human Phelan-McDermid syndrome (22q13.3 deletion...
Autores principales: | Liu, Chun-xue, Peng, Xiao-lan, Hu, Chun-chun, Li, Chun-yang, Li, Qiang, Xu, Xiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099374/ https://www.ncbi.nlm.nih.gov/pubmed/27562614 http://dx.doi.org/10.1007/s00427-016-0561-4 |
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