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Nrf2 and Notch Signaling in Lung Cancer: Near the Crossroad

The transcription factor Nrf2 (NF-E2 related factor 2) is a master regulator of the cell antioxidant response associated with tumor growth and resistance to cytotoxic treatments. In particular, Nrf2 induces upregulation of cytoprotective genes by interacting with the closely situated AREs (Antioxida...

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Detalles Bibliográficos
Autores principales: Sparaneo, Angelo, Fabrizio, Federico Pio, Muscarella, Lucia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099458/
https://www.ncbi.nlm.nih.gov/pubmed/27847554
http://dx.doi.org/10.1155/2016/7316492