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A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis

2-C-Methyl-D-erythritol-4-phosphate cytidyltransferase (IspD) is an essential enzyme in the mevalonate-independent pathway of isoprenoid biosynthesis. This enzyme catalyzes 2-C-Methyl-d-erythritol 4-phosphate (MEP) and cytosine triphosphate (CTP) to 4-diphosphocytidyl-2-C-methyl-d-erythritol (CDPME)...

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Detalles Bibliográficos
Autores principales: Jin, Yun, Liu, Zhongchuan, Li, Yanjie, Liu, Weifeng, Tao, Yong, Wang, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099578/
https://www.ncbi.nlm.nih.gov/pubmed/27821871
http://dx.doi.org/10.1038/srep36379