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Combined Treatment With Environmental Enrichment and (-)-Epigallocatechin-3-Gallate Ameliorates Learning Deficits and Hippocampal Alterations in a Mouse Model of Down Syndrome

Intellectual disability in Down syndrome (DS) is accompanied by altered neuro-architecture, deficient synaptic plasticity, and excitation-inhibition imbalance in critical brain regions for learning and memory. Recently, we have demonstrated beneficial effects of a combined treatment with green tea e...

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Detalles Bibliográficos
Autores principales: Catuara-Solarz, Silvina, Espinosa-Carrasco, Jose, Erb, Ionas, Langohr, Klaus, Gonzalez, Juan Ramon, Notredame, Cedric, Dierssen, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099603/
https://www.ncbi.nlm.nih.gov/pubmed/27844057
http://dx.doi.org/10.1523/ENEURO.0103-16.2016