The role of P2X7 receptors in a rodent PCP-induced schizophrenia model

P2X7 receptors (P2X7Rs) are ligand-gated ion channels sensitive to extracellular ATP. Here we examined for the first time the role of P2X7R in an animal model of schizophrenia. Using the PCP induced schizophrenia model we show that both genetic deletion and pharmacological inhibition of P2X7Rs allev...

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Detalles Bibliográficos
Autores principales: Koványi, Bence, Csölle, Cecilia, Calovi, Stefano, Hanuska, Adrienn, Kató, Erzsébet, Köles, László, Bhattacharya, Anindya, Haller, József, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099752/
https://www.ncbi.nlm.nih.gov/pubmed/27824163
http://dx.doi.org/10.1038/srep36680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099752/
https://www.ncbi.nlm.nih.gov/pubmed/27824163
http://dx.doi.org/10.1038/srep36680

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