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Engineered Nanomedicine with Alendronic Acid Corona Improves Targeting to Osteosarcoma
We engineered nanomedicine with the stealth corona made up of densely packed bone seeking ligand, alendronic acid. In a typical nanoconstruct, alendronic acid is conjugated with hydrophilic head moiety of phospholipid that has an ability to self-assemble with hydrophobic polymeric core through its h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099855/ https://www.ncbi.nlm.nih.gov/pubmed/27824143 http://dx.doi.org/10.1038/srep36707 |