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Engineered Nanomedicine with Alendronic Acid Corona Improves Targeting to Osteosarcoma

We engineered nanomedicine with the stealth corona made up of densely packed bone seeking ligand, alendronic acid. In a typical nanoconstruct, alendronic acid is conjugated with hydrophilic head moiety of phospholipid that has an ability to self-assemble with hydrophobic polymeric core through its h...

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Detalles Bibliográficos
Autores principales: Nguyen, Tuyen Duong Thanh, Pitchaimani, Arunkumar, Aryal, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099855/
https://www.ncbi.nlm.nih.gov/pubmed/27824143
http://dx.doi.org/10.1038/srep36707