Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization

Sterol regulatory element-binding protein (SREBP) transcription factors are master regulators of cellular lipid homeostasis in mammals and oxygen-responsive regulators of hypoxic adaptation in fungi. SREBP C-terminus binds to the WD40 domain of SREBP cleavage-activating protein (SCAP), which confers...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Xin, Qian, Hongwu, Shao, Wei, Li, Jingxian, Wu, Jianping, Liu, Jun-Jie, Li, Wenqi, Wang, Hong-Wei, Espenshade, Peter, Yan, Nieng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099872/
https://www.ncbi.nlm.nih.gov/pubmed/27811944
http://dx.doi.org/10.1038/cr.2016.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099872/
https://www.ncbi.nlm.nih.gov/pubmed/27811944
http://dx.doi.org/10.1038/cr.2016.123

Ejemplares similares