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Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis

Gastric carcinoma (GC) is the second leading cause of cancer-related mortality worldwide. The efficacy of standard chemotherapy for GC, such as cisplatin (CDDP), is dissatisfactory partly due to the toxic/side-effects. Sulforaphane (SFN), which exhibits effective anti-cancer functions, is a phytoche...

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Detalles Bibliográficos
Autores principales: Wang, Xingxing, Li, Yuan, Dai, Yi, Liu, Qinqiang, Ning, Shilong, Liu, Jiao, Shen, Zhaoxia, Zhu, Dongmei, Jiang, Fei, Zhang, Jianping, Li, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099878/
https://www.ncbi.nlm.nih.gov/pubmed/27824145
http://dx.doi.org/10.1038/srep36796