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Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation

Cortex lycii radicis is the dried root bark of Lycium chinense, a traditional Chinese herb used in multiple ailments. The crude extract of Cortex lycii radicis has growth inhibition effect on GBM cells. Kukoamine A (KuA) is a spermine alkaloid derived from it. KuA possesses antioxidant, anti-inflamm...

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Detalles Bibliográficos
Autores principales: Wang, Qiaoping, Li, Haiyan, Sun, Zhen, Dong, Lihua, Gao, Ling, Liu, Chunlan, Wang, Xiujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099904/
https://www.ncbi.nlm.nih.gov/pubmed/27824118
http://dx.doi.org/10.1038/srep36543