DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis

Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase of collagen, is primarily expressed in epithelial cells. Activation of DDR1 stabilises E-cadherin located on the cell membrane; however, the detailed mechanism of DDR1-stabilised E-cadherin remains unclear. We performed DDR1 knockdown (S...

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Detalles Bibliográficos
Autores principales: Chen, Hong-Ru, Yeh, Yi-Chun, Liu, Ching-Yi, Wu, Yu-Ting, Lo, Fang-Yu, Tang, Ming-Jer, Wang, Yang-Kao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099905/
https://www.ncbi.nlm.nih.gov/pubmed/27824116
http://dx.doi.org/10.1038/srep36336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099905/
https://www.ncbi.nlm.nih.gov/pubmed/27824116
http://dx.doi.org/10.1038/srep36336

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