Cargando…
Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation
Invadopodia, actin-based protrusions of invasive carcinoma cells that focally activate extracellular matrix-degrading proteases, are essential for the migration and intravasation of tumor cells during dissemination from the primary tumor. We have previously shown that cortactin phosphorylation at ty...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099927/ https://www.ncbi.nlm.nih.gov/pubmed/27824079 http://dx.doi.org/10.1038/srep36142 |