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Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues

It is commonly assumed that drug targets are expressed in tissues relevant to their indicated diseases, even under normal conditions. While multiple anecdotal cases support this hypothesis, a comprehensive study has not been performed to verify it. We conducted a systematic analysis to assess gene a...

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Detalles Bibliográficos
Autores principales: Kumar, Vinod, Sanseau, Philippe, Simola, Daniel F., Hurle, Mark R., Agarwal, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099936/
https://www.ncbi.nlm.nih.gov/pubmed/27824084
http://dx.doi.org/10.1038/srep36205