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Design, synthesis and biological evaluation of hybrids of β-carboline and salicylic acid as potential anticancer and apoptosis inducing agents

A novel series of hybrids (7a-l, 8a-l) from β-carboline and salicylic acid (SA) were designed and synthesized, and their in vitro biological activities were evaluated. Most of the hybrids displayed potent antiproliferative activity against five cancer cell lines in vitro, showing potencies superior...

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Detalles Bibliográficos
Autores principales: Xu, Qi-Bing, Chen, Xiang-Fan, Feng, Jiao, Miao, Jie-Fei, Liu, Ji, Liu, Feng-Tao, Niu, Bi-Xi, Cai, Jin-Yang, Huang, Chao, Zhang, Yanan, Ling, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099944/
https://www.ncbi.nlm.nih.gov/pubmed/27824091
http://dx.doi.org/10.1038/srep36238