Cargando…
Design, synthesis and biological evaluation of hybrids of β-carboline and salicylic acid as potential anticancer and apoptosis inducing agents
A novel series of hybrids (7a-l, 8a-l) from β-carboline and salicylic acid (SA) were designed and synthesized, and their in vitro biological activities were evaluated. Most of the hybrids displayed potent antiproliferative activity against five cancer cell lines in vitro, showing potencies superior...
Autores principales: | Xu, Qi-Bing, Chen, Xiang-Fan, Feng, Jiao, Miao, Jie-Fei, Liu, Ji, Liu, Feng-Tao, Niu, Bi-Xi, Cai, Jin-Yang, Huang, Chao, Zhang, Yanan, Ling, Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099944/ https://www.ncbi.nlm.nih.gov/pubmed/27824091 http://dx.doi.org/10.1038/srep36238 |
Ejemplares similares
-
Design, Synthesis, and Biological Evaluation of Novel N-Acylhydrazone Bond Linked Heterobivalent β-Carbolines as Potential Anticancer Agents
por: Chen, Xiaofei, et al.
Publicado: (2019) -
Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents
por: Voggu, Ramakrishna, et al.
Publicado: (2023) -
Molecular docking analysis of α-Topoisomerase II with δ-Carboline derivatives as potential anticancer agents
por: Ayyamperumal, Selvaraj, et al.
Publicado: (2021) -
3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents
por: Ribeiro, João L. P., et al.
Publicado: (2022) -
β-Carboline copper complex as a potential mitochondrial-targeted anticancer chemotherapeutic agent: Favorable attenuation of human breast cancer MCF7 cells via apoptosis
por: Khan, Rais Ahmad, et al.
Publicado: (2020)