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Transcriptional coactivator NT‐PGC‐1α promotes gluconeogenic gene expression and enhances hepatic gluconeogenesis

The transcriptional coactivator PGC‐1α plays a central role in hepatic gluconeogenesis. We previously reported that alternative splicing of the PGC‐1α gene produces an additional transcript encoding the truncated protein NT‐PGC‐1α. NT‐PGC‐1α is co‐expressed with PGC‐1α and highly induced by fasting...

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Detalles Bibliográficos
Autores principales: Chang, Ji Suk, Jun, Hee‐Jin, Park, Minsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099968/
https://www.ncbi.nlm.nih.gov/pubmed/27798359
http://dx.doi.org/10.14814/phy2.13013