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Direct proof of spontaneous translocation of lipid-covered hydrophobic nanoparticles through a phospholipid bilayer

Hydrophobic nanoparticles introduced into living systems may lead to increased toxicity, can activate immune cells, or can be used as nanocarriers for drug or gene delivery. It is generally accepted that small hydrophobic nanoparticles are blocked by lipid bilayers and accumulate in the bilayer core...

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Detalles Bibliográficos
Autores principales: Guo, Yachong, Terazzi, Emmanuel, Seemann, Ralf, Fleury, Jean Baptiste, Baulin, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099980/
https://www.ncbi.nlm.nih.gov/pubmed/27847863
http://dx.doi.org/10.1126/sciadv.1600261