Connecting the Sequence-Space of Bacterial Signaling Proteins to Phenotypes Using Coevolutionary Landscapes

Two-component signaling (TCS) is the primary means by which bacteria sense and respond to the environment. TCS involves two partner proteins working in tandem, which interact to perform cellular functions whereas limiting interactions with non-partners (i.e., cross-talk). We construct a Potts model...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, R. R., Nordesjö, O., Hayes, R. L., Levine, H., Flores, S. C., Onuchic, J. N., Morcos, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Fast Track
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100047/
https://www.ncbi.nlm.nih.gov/pubmed/27604223
http://dx.doi.org/10.1093/molbev/msw188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100047/
https://www.ncbi.nlm.nih.gov/pubmed/27604223
http://dx.doi.org/10.1093/molbev/msw188

Ejemplares similares