Autoregressive transitional ordinal model to test for treatment effect in neurological trials with complex endpoints

BACKGROUND: A number of potential therapeutic approaches for neurological disorders have failed to provide convincing evidence of efficacy, prompting pharmaceutical and health companies to discontinue their involvement in drug development. Limitations in the statistical analysis of complex endpoints...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanadini, Lorenzo G., Steeves, John D., Curt, Armin, Hothorn, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100172/
https://www.ncbi.nlm.nih.gov/pubmed/27821067
http://dx.doi.org/10.1186/s12874-016-0251-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100172/
https://www.ncbi.nlm.nih.gov/pubmed/27821067
http://dx.doi.org/10.1186/s12874-016-0251-y

Ejemplares similares