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Spontaneous mutations in the flhD operon generate motility heterogeneity in Escherichia coli biofilm

BACKGROUND: Heterogeneity and niche adaptation in bacterial biofilm involve changes to the genetic makeup of the bacteria and gene expression control. We hypothesized that i) spontaneous mutations in the flhD operon can either increase or decrease motility and that ii) the resulting motility heterog...

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Detalles Bibliográficos
Autores principales: Horne, Shelley M., Sayler, Joseph, Scarberry, Nicholas, Schroeder, Meredith, Lynnes, Ty, Prüß, Birgit M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100188/
https://www.ncbi.nlm.nih.gov/pubmed/27821046
http://dx.doi.org/10.1186/s12866-016-0878-1