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Limited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast Asia
BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged as a major threat for malaria control and elimination worldwide. Mutations in the Kelch propeller domain of PfK13 are the only known molecular markers for artemisinin resistance in this parasite. Over 100 non-synonymous mutation...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100195/ https://www.ncbi.nlm.nih.gov/pubmed/27821166 http://dx.doi.org/10.1186/s12936-016-1583-0 |