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Limited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast Asia

BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged as a major threat for malaria control and elimination worldwide. Mutations in the Kelch propeller domain of PfK13 are the only known molecular markers for artemisinin resistance in this parasite. Over 100 non-synonymous mutation...

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Detalles Bibliográficos
Autores principales:	Wang, Meilian, Siddiqui, Faiza Amber, Fan, Qi, Luo, Enjie, Cao, Yaming, Cui, Liwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100195/ https://www.ncbi.nlm.nih.gov/pubmed/27821166 http://dx.doi.org/10.1186/s12936-016-1583-0

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