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Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation

BACKGROUND: The transcription factor SOX10 is essential for all stages of Schwann cell development including myelination. SOX10 cooperates with other transcription factors to activate the expression of key myelin genes in Schwann cells and is therefore a context-dependent, pro-myelination transcript...

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Detalles Bibliográficos
Autores principales: Gopinath, Chetna, Law, William D., Rodríguez-Molina, José F., Prasad, Arjun B., Song, Lingyun, Crawford, Gregory E., Mullikin, James C., Svaren, John, Antonellis, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100263/
https://www.ncbi.nlm.nih.gov/pubmed/27821050
http://dx.doi.org/10.1186/s12864-016-3167-3