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Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential

BACKGROUND: Osteosarcoma (OS), which has a high potential for developing metastatic disease, is the most frequent malignant bone tumor in children and adolescents. Molecular analysis of a metastatic genetically engineered mouse model of osteosarcoma identified enhanced expression of Secreted Frizzle...

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Detalles Bibliográficos
Autores principales: Techavichit, Piti, Gao, Yang, Kurenbekova, Lyazat, Shuck, Ryan, Donehower, Lawrence A., Yustein, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100268/
https://www.ncbi.nlm.nih.gov/pubmed/27821163
http://dx.doi.org/10.1186/s12885-016-2909-6