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HMGB2 holds the key to the senescence-associated secretory phenotype

The senescence-associated secretory phenotype (SASP) is a hallmark of senescence with an important physiological impact, but how it is established is unclear. In this issue, Aird et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201608026) describe how chromatin-bound HMGB2 fine tunes SASP exp...

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Detalles Bibliográficos
Autores principales: Guerrero, Ana, Gil, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100298/
https://www.ncbi.nlm.nih.gov/pubmed/27799373
http://dx.doi.org/10.1083/jcb.201610044