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A painful TR(i)P to lysosomes

The ion channel TRPA1 detects noxious stimuli at the plasma membrane of neurons and elicits pain and inflammation. In this issue, Shang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603081) report that TRPA1 also localizes to lysosomal membranes of neurons, releasing intracellular Ca(...

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Detalles Bibliográficos
Autores principales: Gu, Mingxue, Xu, Haoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100301/
https://www.ncbi.nlm.nih.gov/pubmed/27799365
http://dx.doi.org/10.1083/jcb.201610067