A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses

Overproduction or poor clearance of amyloids lead to amyloid aggregation and even amyloidosis development. Different amyloids may interact synergistically to promote their aggregation and accelerate pathology in amyloidoses. Amyloid oligomers assembled from different amyloids share common structures...

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Detalles Bibliográficos
Autores principales: Zha, Jun, Liu, Xiang-meng, Zhu, Jie, Liu, Shu-ying, Lu, Shuai, Xu, Peng-xin, Yu, Xiao-lin, Liu, Rui-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100551/
https://www.ncbi.nlm.nih.gov/pubmed/27824125
http://dx.doi.org/10.1038/srep36631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100551/
https://www.ncbi.nlm.nih.gov/pubmed/27824125
http://dx.doi.org/10.1038/srep36631

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