Entropic stabilization of folded RNA in crowded solutions measured by SAXS

Non-coding RNAs must fold into specific structures that are stabilized by metal ions and other co-solutes in the cell's interior. Large crowder molecules such as PEG stabilize a bacterial group I ribozyme so that the RNA folds in low Mg(2+) concentrations typical of the cell's interior. To...

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Detalles Bibliográficos
Autores principales: Kilburn, Duncan, Behrouzi, Reza, Lee, Hui-Ting, Sarkar, Krishnarjun, Briber, Robert M., Woodson, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100557/
https://www.ncbi.nlm.nih.gov/pubmed/27378777
http://dx.doi.org/10.1093/nar/gkw597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100557/
https://www.ncbi.nlm.nih.gov/pubmed/27378777
http://dx.doi.org/10.1093/nar/gkw597

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