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Entropic stabilization of folded RNA in crowded solutions measured by SAXS
Non-coding RNAs must fold into specific structures that are stabilized by metal ions and other co-solutes in the cell's interior. Large crowder molecules such as PEG stabilize a bacterial group I ribozyme so that the RNA folds in low Mg(2+) concentrations typical of the cell's interior. To...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100557/ https://www.ncbi.nlm.nih.gov/pubmed/27378777 http://dx.doi.org/10.1093/nar/gkw597 |